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Joint Pain & Arthritis · Concern

Shoulder Arthritis

Pain reaching overhead and the inability to sleep on that side are the hallmarks of shoulder arthritis. PHI's board-certified physicians offer image-guided injections and regenerative medicine, with honest diagnosis of whether the rotator cuff is also involved.

Medically Reviewed By
Nadiv Y. Samimi
Faisal Lalani
Nadiv Y. Samimi, MD & Faisal Lalani, MD MD
Last reviewed · June 4, 2026
IN SHORT

Shoulder arthritis is cartilage wear in the shoulder joint that causes pain with reaching and difficulty sleeping on that side. At PHI in Beverly Hills, board-certified physicians Dr. Faisal Lalani and Dr. Nadiv Samimi offer image-guided shoulder injections and regenerative medicine, with honest guidance on whether arthritis or the rotator cuff is driving your pain.

When Your Shoulder Decides You Can’t Sleep On That Side

Shoulder arthritis tends to announce itself in specific ways. Pain when you reach overhead. Difficulty putting on a shirt or jacket. The realization that you cannot sleep on that shoulder anymore. Tennis or golf shots that do not feel right. Hairstyling, reaching for items on shelves, or buckling a seatbelt becomes an effort.

Many shoulder arthritis patients are surprised by how much the condition affects sleep. The shoulder is non-weight-bearing during the day, but lying on it at night puts pressure on the arthritic joint, and patients often describe waking up repeatedly trying to find a comfortable position. Most patients we see have been told either that they will need a replacement eventually or that there is nothing to do but modify activities and take anti-inflammatories. Both framings skip over the meaningful treatment options that exist at most stages.

What Shoulder Arthritis Actually Is

Your shoulder is the most mobile joint in your body. The term shoulder arthritis usually refers to the glenohumeral joint, where the head of your humerus sits in the shallow socket of your shoulder blade. This joint trades stability for mobility: the shallow socket allows enormous range of motion but relies heavily on surrounding structures, especially the rotator cuff, for stability. When arthritis develops, the cartilage between the bones wears down, producing pain, stiffness, and reduced range of motion.

Common forms include glenohumeral osteoarthritis (the most common), rheumatoid and other inflammatory arthritis (coordinated with rheumatology), post-traumatic arthritis, cuff tear arthropathy (which develops after long-standing rotator cuff tears), and acromioclavicular joint arthritis at the top of the shoulder. Each requires somewhat different evaluation and treatment.

A Common Diagnostic Question, Arthritis or Rotator Cuff?

One of the most common diagnostic questions for shoulder pain in patients over 50 is whether the primary issue is arthritis, a rotator cuff problem, or both. The two often coexist, and patients labeled with shoulder arthritis sometimes have rotator cuff issues that are actually more responsible for their symptoms.

Treatment recommendations vary significantly based on which is dominant. PRP for rotator cuff tendinopathy is different from regenerative treatment for arthritis. Knowing which is driving the pain matters, which is part of why thorough evaluation matters. Many shoulder pain patients arrive having been treated for the wrong primary diagnosis. Common features of shoulder arthritis include pain with overhead activities, night pain when lying on the affected side, gradual stiffness and reduced range of motion, deep pain rather than at a specific surface point, and cracking or grinding with movement.

How PHI Treats Shoulder Arthritis

Treatment begins with a comprehensive evaluation: a detailed history, an examination assessing range of motion, strength, and patterns suggesting joint versus rotator cuff involvement, and review of imaging. Based on that, options include:

Image-guided shoulder injections with cortisone for inflammation. The shoulder is a joint where image guidance significantly improves accuracy because surface landmarks often misidentify the precise target, so PHI uses image guidance for every shoulder injection, with cortisone’s cumulative considerations discussed honestly. PRP therapy, particularly useful for shoulders with combined arthritis and rotator cuff components. A2M therapy, which neutralizes cartilage-destroying enzymes and is relevant for early-to-moderate arthritis. Stem cell therapy for moderate to severe arthritis or after PRP. Exosome therapy within comprehensive protocols. When shoulder replacement is appropriate, we coordinate with orthopedic specialists; modern reverse shoulder arthroplasty has made replacement possible for patients with cuff tear arthropathy who previously had few options.

When to See Someone

Consider professional evaluation when your shoulder pain has lasted more than four to six weeks without improvement, when it interferes with sleep or daily activities, when you are avoiding overhead activities or work tasks, when you want to understand non-surgical options, or when you are considering replacement and want to explore alternatives first.

Seek prompt evaluation if you experience sudden severe shoulder pain following an injury, significant new weakness in the arm, inability to lift the arm, or significant joint swelling, warmth, or redness.

Why PHI for Shoulder Arthritis

i.

Two board-certified pain physicians

Dr. Faisal Lalani and Dr. Nadiv Samimi both trained in interventional pain at Cedars-Sinai, with specific expertise in image-guided shoulder injections and the full range of regenerative options.

ii.

Image-guided shoulder injections

Many practices perform shoulder injections without imaging, which significantly reduces accuracy. PHI uses image guidance in our affiliated surgical suite for every shoulder injection.

iii.

Diagnostic clarity between arthritis and rotator cuff

We take time to identify whether your shoulder pain is primarily arthritis, primarily rotator cuff, or both, which significantly affects treatment recommendations.

iv.

Full regenerative menu

PHI offers PRP, A2M, multiple stem cell protocols, and exosome therapy. The right option for your specific shoulder condition may not be the one a single-modality practice happens to offer.

v.

Coordination with surgical specialists

When shoulder replacement, including modern reverse arthroplasty, is appropriate, we coordinate orthopedic referral.

vi.

Concierge, coordinated care

Single-physician continuity from consultation through treatment and return to activity. Patients receive clear guidance and transparent pricing at consultation.

Frequently Asked Questions

Shoulder arthritis specifically involves cartilage breakdown in the joint. Rotator cuff problems involve the muscles and tendons that surround and stabilize the shoulder. The two often coexist, and patients sometimes have one labeled as the cause when the other is actually more responsible. Treatment approaches differ significantly, so identifying which is dominant matters.

Treatments We Offer for Shoulder Arthritis

PHI offers the full range of evidence-based treatments for shoulder arthritis. Your physician will recommend the right option, or combination, based on the stage of your arthritis, whether other shoulder structures are involved, your goals, and your treatment history.

Schedule Your Shoulder Arthritis Consultation

A 60-minute consultation will identify what stage of shoulder arthritis you are dealing with, whether other shoulder structures are involved, walk through the treatment options that match your situation, and give you a clear plan. Call (310) 856-9488 or book online now.

Begin a consultation

Schedule with PHI.

A 60-minute consultation includes history, imaging review, and an honest discussion of whether interventional or regenerative care is the right next step for you.