Peripheral neuropathy is damage or dysfunction of the nerves outside the brain and spinal cord, usually felt as burning, tingling, or numbness in the hands and feet. At PHI in Beverly Hills, board-certified physicians Dr. Faisal Lalani and Dr. Nadiv Samimi offer targeted nerve blocks and regenerative options alongside management of the underlying cause.
When Your Nerves Don’t Work the Way They Should
Neuropathy has a way of changing daily life that is hard to convey unless you live with it: the persistent burning, tingling, or numbness in your hands or feet, the pins and needles that come and go without warning, the way light touch from a sock or sheet can feel uncomfortable, and the disrupted sleep when symptoms flare at night.
Most neuropathy patients we see have been dealing with these symptoms for years. Many are on gabapentin, pregabalin, duloxetine, or similar medications that produce partial relief along with side effects, and many have been told there is not much else to do. What we offer is a comprehensive evaluation of your specific situation and access to interventional and supportive treatments that may complement your existing care. We are honest that neuropathy treatment is challenging and that not every approach works for every patient, and also that some patients find meaningful relief through options they have not yet tried.
What Neuropathy Actually Is
Peripheral neuropathy refers to damage or dysfunction of nerves outside the brain and spinal cord, typically affecting the hands and feet first because the longest nerves in your body run there. The damaged nerves can no longer transmit signals normally, which produces the characteristic symptoms.
Common patterns include burning or shooting pain (often in the feet and hands), numbness or reduced sensation, tingling or pins-and-needles, hypersensitivity where light touch or temperature change becomes uncomfortable, unusual temperature sensations, weakness in affected muscles, balance problems when sensory feedback from the feet is affected, and symptoms that often worsen at night or with rest. The pattern, severity, and progression depend significantly on the underlying cause.
Why Neuropathy Develops
Many conditions can damage peripheral nerves. Diabetes is the leading cause worldwide, with high blood sugar over time damaging the small blood vessels supplying nerves. Chemotherapy can cause neuropathy as a side effect of certain cancer treatments. Vitamin deficiencies, particularly B12, can produce neuropathy that may improve with appropriate supplementation if caught early. Alcohol use over time, autoimmune conditions, hereditary conditions, kidney and thyroid disorders, infections, and toxin exposure are other contributors, and a substantial portion of patients have idiopathic neuropathy in whom no specific cause is identified.
Identifying and treating the underlying cause is the most important step. PHI works alongside your primary care physician, endocrinologist, or neurologist for that aspect of care while providing complementary interventional options. We do not replace your existing care team; we add specific options that may help where standard approaches have not been enough.
How PHI Approaches Neuropathy
The first step is comprehensive evaluation: a detailed history of your neuropathy and how it has progressed, confirmation of any underlying diagnosis, review of your current treatment and providers, and an honest assessment of which interventional or supportive options may be appropriate.
Targeted nerve blocks can help selected patients with focal neuropathy patterns or specific nerve entrapments, and can also identify whether specific nerves are involved beyond generalized neuropathy; we are honest that they are not a primary treatment for diffuse peripheral neuropathy. Regenerative options including PRP, stem cell, A2M, and exosome therapy are sometimes pursued; honest framing matters here, because the evidence for regenerative medicine in peripheral neuropathy specifically is more limited than in joint conditions, and we discuss realistic expectations rather than presenting these as established cures. Effective neuropathy management typically requires coordination across multiple providers, and we work with your existing team rather than duplicating their care.
Why PHI for Neuropathy
Two board-certified pain physicians
Dr. Faisal Lalani and Dr. Nadiv Samimi both trained in interventional pain at Cedars-Sinai, with experience across various underlying causes of neuropathy.
Surgical suite
Procedures are performed by PHI physicians in our affiliated surgical suite under image guidance.
Honest framing
Neuropathy treatment is genuinely challenging. We do not oversell options with limited evidence for this specific condition; we recommend treatments only when they fit your particular situation.
Coordinated approach
Effective neuropathy management requires multiple specialists. We work alongside your primary care physician, endocrinologist, or neurologist rather than in isolation.
A range of supportive options
PHI offers targeted nerve blocks and the full regenerative menu. The right combination depends on your specific situation, and for some patients combinations make sense.
Concierge, coordinated care
Single-physician continuity from consultation through treatment and return to activity. Patients receive clear guidance and transparent pricing at consultation.
Frequently Asked Questions
This depends entirely on the underlying cause and how long it has persisted. Some neuropathy improves significantly with treatment of the underlying cause, such as B12 deficiency corrected with supplementation or blood sugar brought under tight control early in diabetes. Other neuropathies are more persistent. Treatments aim to manage symptoms and slow progression rather than fully reverse the condition in most cases.
The evidence for regenerative medicine specifically in peripheral neuropathy is more limited than the evidence for these treatments in joint conditions. Some patients report meaningful improvement with PRP, stem cell, or exosome therapy; others do not experience benefit. We discuss this honestly and do not position regenerative medicine as an established cure for neuropathy.
Generally yes, unless your prescribing physician indicates otherwise. PHI’s interventional options typically work alongside standard medications rather than replacing them. Some patients can reduce doses if interventional treatments produce significant relief, but this is a coordinated decision with your prescribing physician.
Chemotherapy-induced neuropathy has its own characteristics and treatment considerations. PHI sees chemotherapy-induced neuropathy patients and coordinates with your oncology team. Approaches depend on whether you are in active treatment, in remission, or post-treatment.
This depends on the severity and duration of your neuropathy. Some patients experience improved sensation and balance with treatment of underlying causes and supportive interventions. Patients with longer-standing severe neuropathy may have more limited functional improvement, and physical therapy with balance training is often an important component of comprehensive care.
Yes, though more advanced cases are typically more challenging. Even advanced neuropathy patients often experience meaningful symptom reduction with appropriate care, even if full reversal is not possible. The goal is improved quality of life and slowing progression rather than eliminating the condition entirely.
Neurologists handle the diagnosis, underlying condition management, and standard medication management. PHI provides interventional and regenerative options that complement neurology care. Many patients benefit from both, and we coordinate with your neurologist rather than replacing that care.
Insurance coverage and payment options may vary. Please contact our office to discuss your specific plan, available options, and pricing. All pricing is disclosed at consultation.
Yes. PHI regularly treats patients from outside Los Angeles, including Las Vegas, Palm Springs, London, and other international locations.
Treatments We Offer for Neuropathy
PHI offers evidence-based and supportive treatments for neuropathy as part of broader coordinated care. Your physician will recommend the right options based on your underlying cause, symptom pattern, and treatment history.
- Nerve Blocks, for focal patterns or specific nerve entrapments
- PRP Therapy
- Stem Cell Therapy
- A2M Therapy
- Exosome Therapy
Schedule Your Neuropathy Consultation
A 60-minute consultation will evaluate your specific neuropathy situation, walk through the interventional and supportive options that may complement your existing care, and coordinate with your other providers. Call (310) 856-9488 or book online now.