--- title: "NAD+ Therapy" --- ## What NAD+ Is Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in every cell of the body. It plays an essential role in three areas of cellular function: energy production through mitochondrial metabolism, DNA repair, and longevity signaling through pathways involving sirtuins and other regulatory proteins. NAD+ levels decline naturally with age. By age 50, cellular NAD+ levels are estimated to be roughly half of what they were in youth. This decline is associated with reduced cellular energy, impaired DNA repair, and increased markers of biological aging. NAD+ therapy supplements the body's NAD+ pool through direct administration. Unlike oral NAD+ precursors (NMN, NR), which must be converted by the body, IV and IM NAD+ delivers the molecule itself in usable form. ## How PHI Approaches NAD+ Therapy NAD+ therapy at PHI is physician-prescribed, not menu-selected. PHI's approach starts with consultation to determine whether NAD+ therapy fits your specific goals and which protocol is appropriate. The reason this matters: NAD+ therapy at meaningful therapeutic doses can produce side effects (chest pressure, flushing, nausea) particularly during initial infusions, and tolerance varies significantly by individual. PHI's protocols are tiered intentionally, starting at lower doses for new patients and progressing only as tolerance is established. Patients who would benefit more from a different intervention are told so. NAD+ is a powerful tool when it fits, but it is not the right answer for every patient pursuing wellness or longevity goals. https://youtube.com/shorts/Gn7Cws6fPKk?si=QCeYVn9JddEwB6JT ## PHI's NAD+ Protocols and Pricing NAD+ therapy cost in Beverly Hills varies by protocol. PHI publishes pricing for transparency, with five tiered options designed for therapeutic initiation, ongoing optimization, and maintenance. #### Intramuscular NAD+ shots IM injections offer a practical, time-efficient option for sustaining NAD+ levels between IV sessions, ideal for patients on active optimization protocols. **NAD+ Shot 50 mg | $95** (first-timer, intramuscular). An ideal introduction to NAD+ therapy, delivered intramuscularly for rapid uptake with minimal time commitment. **NAD+ Shot 100 mg | $170** (regular user, intramuscular). Recommended for established NAD+ users maintaining levels between IV infusion sessions. #### Intravenous NAD+ infusions IV delivery provides complete bioavailability and systemic distribution. All IV protocols include 500 mL of hydration and electrolytes. **NAD+ IV Lite 250 mg | $400** (first-timer, up to 2 hours). The recommended starting point for IV therapy, allowing tolerance assessment at a therapeutic dose before progressing to higher concentrations. **NAD+ IV Plus 500 mg | $700** (regular use, up to 4 hours, recommended). PHI's standard therapeutic protocol for ongoing optimization, energy restoration, and cellular repair, and the most-prescribed protocol for established patients. **NAD+ IV Ultra 1,000 mg | $1,000** (experienced, up to 6 hours). Reserved for experienced patients seeking maximum cellular replenishment and longevity benefit, appropriate only after lower-tier tolerance is established. ## Choosing the Right Protocol - New to NAD+ therapy: most patients begin with a 50 mg IM shot or the IV Lite (250 mg) to assess tolerance. - Active optimization: the IV Plus (500 mg) is PHI's most-prescribed protocol, often paired with 100 mg IM shots between infusions. - Advanced longevity protocols: the IV Ultra (1,000 mg) is reserved for experienced patients with established tolerance, typically as part of a comprehensive longevity program. Frequency is individualized. Some patients pursue weekly or biweekly infusions during initiation, then transition to monthly maintenance with IM shots between sessions. ## Why Patients Choose PHI for NAD+ Therapy ## What to Expect ## Frequently Asked Questions **Q: Is NAD+ therapy FDA-approved?** NAD+ is administered as a compounded preparation through licensed compounding pharmacies under FDA section 503A. NAD+ itself is not FDA-approved as a drug for specific indications, which is consistent with most regenerative and longevity therapies. **Q: How is IV NAD+ different from oral NAD+ precursors like NMN or NR?** Oral NAD+ precursors (NMN, NR) must be converted by the body into usable NAD+, with variable bioavailability and a conversion pathway that may reduce effective dose. IV and IM NAD+ delivers the molecule itself, bypassing conversion. **Q: How will I feel during my first NAD+ infusion?** Most patients experience some sensation during their first infusion, often described as chest pressure, warmth, or mild nausea. These effects are dose- and rate-dependent, and slowing the infusion typically reduces or resolves them. PHI starts new patients at lower doses (Lite 250 mg) specifically to assess and manage tolerance. **Q: How quickly will I feel benefits?** This varies by individual and protocol. Some patients report increased energy and mental clarity within hours of an IV infusion; others notice more gradual effects over a series of sessions. Longevity benefits develop over longer timeframes and are not directly perceptible. **Q: How often should I receive NAD+ therapy?** Frequency depends on your goals. Initiation protocols often involve weekly or biweekly IV infusions for several weeks, while maintenance protocols typically use monthly IV infusions or weekly IM shots. Your physician will design a schedule based on your goals and response. **Q: Are there risks or contraindications?** NAD+ therapy is generally well-tolerated under physician supervision at appropriate doses. Patients with active cancers, severe kidney or liver disease, or specific cardiovascular conditions require careful screening. NAD+ is not appropriate for everyone, which is why physician evaluation is essential. **Q: Can I eat before my NAD+ infusion?** Yes. NAD+ therapy does not require fasting. A light meal beforehand may help reduce nausea during the infusion. **Q: Does NAD+ therapy reverse aging?** NAD+ therapy supports cellular processes that decline with age (energy production, DNA repair, longevity signaling). It does not reverse aging, but it addresses one of the measurable cellular changes associated with aging. NAD+ is one tool among many in a longevity protocol, not a fountain of youth. **Q: How much does NAD+ therapy cost in Los Angeles?** NAD+ therapy at PHI ranges from $95 for an IM shot to $1,000 for the IV Ultra protocol. Full pricing is published above and confirmed at consultation. Pricing is structured per consultation, per infusion, and for the standard induction series, and all costs are disclosed at consultation with no hidden fees. **Q: Do you accept international patients?** Yes. NAD+ therapy is well-suited to patients traveling to PHI from outside Los Angeles, often as part of comprehensive wellness visits combining NAD+ with peptides, IV protocols, regenerative procedures, or other treatments. ```ld+json { "@context": "https://schema.org", "@graph": [ { "@context": "https://schema.org", "@type": "Service", "@id": "https://painandhealing.com/treatments/nad-therapy/#service", "name": "NAD+ Therapy", "url": "https://painandhealing.com/treatments/nad-therapy/", "description": "Physician-prescribed NAD+ therapy, a coenzyme involved in cellular energy production and DNA repair that declines with age. Used at PHI to support energy, cognitive clarity, and longevity-oriented care. 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PHI offers physician-supervised NAD+ in five tiered protocols, two intramuscular shots and three IV infusions, for cellular energy, DNA repair, and longevity, with doses progressed as tolerance is established." }, "isPartOf": { "@id": "https://painandhealing.com/treatments/nad-therapy/#webpage" }, "url": "https://painandhealing.com/treatments/nad-therapy/" }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Is NAD+ therapy FDA-approved?", "acceptedAnswer": { "@type": "Answer", "text": "

NAD+ is administered as a compounded preparation through licensed compounding pharmacies under FDA section 503A. NAD+ itself is not FDA-approved as a drug for specific indications, which is consistent with most regenerative and longevity therapies.

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Oral NAD+ precursors (NMN, NR) must be converted by the body into usable NAD+, with variable bioavailability and a conversion pathway that may reduce effective dose. IV and IM NAD+ delivers the molecule itself, bypassing conversion.

" } }, { "@type": "Question", "name": "How will I feel during my first NAD+ infusion?", "acceptedAnswer": { "@type": "Answer", "text": "

Most patients experience some sensation during their first infusion, often described as chest pressure, warmth, or mild nausea. These effects are dose- and rate-dependent, and slowing the infusion typically reduces or resolves them. PHI starts new patients at lower doses (Lite 250 mg) specifically to assess and manage tolerance.

" } }, { "@type": "Question", "name": "How quickly will I feel benefits?", "acceptedAnswer": { "@type": "Answer", "text": "

This varies by individual and protocol. Some patients report increased energy and mental clarity within hours of an IV infusion; others notice more gradual effects over a series of sessions. Longevity benefits develop over longer timeframes and are not directly perceptible.

" } }, { "@type": "Question", "name": "How often should I receive NAD+ therapy?", "acceptedAnswer": { "@type": "Answer", "text": "

Frequency depends on your goals. Initiation protocols often involve weekly or biweekly IV infusions for several weeks, while maintenance protocols typically use monthly IV infusions or weekly IM shots. Your physician will design a schedule based on your goals and response.

" } }, { "@type": "Question", "name": "Are there risks or contraindications?", "acceptedAnswer": { "@type": "Answer", "text": "

NAD+ therapy is generally well-tolerated under physician supervision at appropriate doses. Patients with active cancers, severe kidney or liver disease, or specific cardiovascular conditions require careful screening. NAD+ is not appropriate for everyone, which is why physician evaluation is essential.

" } }, { "@type": "Question", "name": "Can I eat before my NAD+ infusion?", "acceptedAnswer": { "@type": "Answer", "text": "

Yes. NAD+ therapy does not require fasting. A light meal beforehand may help reduce nausea during the infusion.

" } }, { "@type": "Question", "name": "Does NAD+ therapy reverse aging?", "acceptedAnswer": { "@type": "Answer", "text": "

NAD+ therapy supports cellular processes that decline with age (energy production, DNA repair, longevity signaling). It does not reverse aging, but it addresses one of the measurable cellular changes associated with aging. NAD+ is one tool among many in a longevity protocol, not a fountain of youth.

" } }, { "@type": "Question", "name": "How much does NAD+ therapy cost in Los Angeles?", "acceptedAnswer": { "@type": "Answer", "text": "

NAD+ therapy at PHI ranges from $95 for an IM shot to $1,000 for the IV Ultra protocol. Full pricing is published above and confirmed at consultation. Pricing is structured per consultation, per infusion, and for the standard induction series, and all costs are disclosed at consultation with no hidden fees.

" } }, { "@type": "Question", "name": "Do you accept international patients?", "acceptedAnswer": { "@type": "Answer", "text": "

Yes. NAD+ therapy is well-suited to patients traveling to PHI from outside Los Angeles, often as part of comprehensive wellness visits combining NAD+ with peptides, IV protocols, regenerative procedures, or other treatments.

" } } ] } ] } ```